Akttyva Therapeutics is looking for several talented individuals to join our growing team in Mansfield, MA.
Computational Scientist. If you have an advanced degree (Ph. D. or M.S.) in biochemistry, structural biology, computational sciences or cheminformatics and are interested in working with leading cheminformatics scientists on advancing our proprietary AI-assisted virtual drug-discovery platform, please apply here: https://careers.massbio.org/job/computational-scientist/60793548/
Biochemistry-Cell Biology Senior Scientist at Akttyva Therapeutics
Akttyva Therapeutics, a recently launched drug-discovery company, is at the forefront of accelerating drug development through innovation and technology. Founded by a distinguished group of pharmaceutical industry veterans, scientists, and entrepreneurs, our mission is to advance the drug discovery process. We have developed an AI-powered drug discovery platform that seamlessly integrates with experimental studies, enhancing our ability to design novel therapeutics efficiently and effectively. At Akttyva Therapeutics, we are committed to pushing the boundaries of science to create solutions that will lead to better health outcomes and affordable treatments worldwide. Join us in our journey to transform the future of medicine. As the Senior Scientist in Biochemistry-Cell Biology at Akttyva Therapeutics, you will develop/optimize cutting-edge in-vitro assays for screening among potential drug candidates, identified through the use of the AIDE360 drug discovery platform.
Key Responsibilities:
· Design and conduct thermal shift assay or other format binding assays, immunoassays, western blotting and other relevant methods to screen experimentally among drug candidates.
· Develop and optimize permeability assays using an endothelial monolayer transwell system and commercially available multicell systems, modeling the air-blood barrier in the lung, to characterize lead drug candidates.
· Maintain and manipulate various cell types in support of drug screening activities and drug development.
· Lead and mentor research associates in experimental design, data analysis, and troubleshooting.
· Collaborate with computational chemist and other scientific teams to support the development of novel therapeutics.
· Analyze and interpret experimental data, presenting findings in internal meetings and external conferences.
· Stay current with the latest scientific literature and technological advancements in drug development and use of AI in drug discovery.
· Contribute to the preparation of scientific manuscripts, patent applications, and grant proposals.
· Ensure compliance with all laboratory safety protocols and maintain accurate records of all research activities.
Qualifications:
• Educational Background: A Ph.D. in Biochemistry, Molecular Biology, Cell Biology or other related field with about 3+ years of relevant experience is required.
• Relevant Experience:
• Strong expertise in protein chemistry and biochemical/biophysical characterization.
• Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR).
• Experience with high-throughput screening.
• Proven track record of success in leading research projects and contributing to scientific publications.
• Excellent problem-solving skills, with the ability to troubleshoot complex biochemical/biological problems.
• Strong communication skills, both written and verbal, with the ability to work effectively in a team-oriented environment.
• Familiarity with regulatory requirements and documentation practices in a biotech or pharmaceutical setting.
• Able to work as part of a team and individually.
How to Apply: If you are passionate about drug discovery projects, we would love to hear from you. Please submit your resume, cover letter, and a portfolio of relevant projects to recruting@akttyva.com
Research Assistant. We are looking for a B.S. / M.S. researcher, who will be working on developing novel in vitro medium- and high-throughput assays to support our drug discovery programs. The assays will involve transformed and primary cell cultures, proteins and cutting-edge organs-on-chip technologies. Familiarity with basic biology / biochemistry laboratory techniques (e.g., electrophoresis, enzyme kinetics, ELISA) and cell culturing techniques is desirable either in academic course work or work experience. https://careers.massbio.org/job/research-assistant/61147972/
Akttyva Therapeutics is offering a competitive salary and benefits package, stock option plan, flexible work schedule, plenty of parking and many opportunities to enhance your career and become a part of an experienced scientific team on exciting projects aiming for revolutionizing drug discovery and development.